Minimally Invasive Glaucoma Surgery (MIGS)

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Last updated 7/25/2024
MIGS, minimally invasive glaucoma surgery, Assil Gaur Eye Institute Los Angeles

What’s Minimally Invasive Glaucoma Surgery (MIGS)?

MIGS incorporates state-of-the-art minimally invasive glaucoma surgeries that use microscopic instruments to facilitate small incision surgery. It provides a safer option to reduce intraocular pressure (IOP) than traditional glaucoma surgery, with the added benefits of a higher success rate and faster recovery time. MIGS present a significantly reduced risk of complications like hypotony, infection and scarring.


The goal of MIGS procedures is to improve fluid drainage out of the eye in patients with mild to moderate glaucoma, reducing the eye pressure that damages the optic nerve. Clinical trials have shown that MIGS procedures achieve a significant decrease in eye pressure over periods of up to 24 months, along with a decrease in prescription eye drop usage.

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The three types of MIGS

 

MIGS procedures fall into three different categories according to how they achieve decreased intraocular pressure:

  • Improving your eye's natural drainage system, known as the trabecular meshwork (iStent, Trabectome, and OMNI360). Similar to a traditional tube shunt. 
  • Redirecting excess ocular fluid outside of your eye (XEN Gel Stent).
  • Decreasing the production of ocular fluid within your eye (Endocyclophotocoagulation).

 

Surgical procedures that decrease eye pressure by improving your eye’s natural drainage pathway 

 

There is a wide range of drainage options for the treatment of glaucoma. These treatment options achieve IOP reduction by increasing the drainage of aqueous humor (ocular fluid) from the eye. These include:

 

iStent Trabecular Micro-Bypass Stent

The iStent is the smallest implantable device approved for use in the human body. It is a titanium device that is implanted at two different sites in the front of your eye to create two bypasses that increase ocular fluid outflow through your eye's natural drainage system. 

 

The iStent is typically implanted at the time of cataract surgery. In clinical trials of the next-generation iStent Inject, most patients were completely off glaucoma medications at 23 months. The stent is made of titanium, so you can safely undergo magnetic resonance imaging (MRI) studies without the risk associated with metal implants.

 

iTrack Canaloplasty

The iTrack repairs the eye's natural drainage system in two ways: First, it uses a micro-catheter to bore a path through the eye's clogged natural drainage canal between the anterior chamber and Schlemm's canal. Next, once the canal has been cleared of debris, a viscoelastic gel is injected into the canal and expands, widening the canal diameter by two to three times its original size. The net result is a greater fluid outflow and decreased eye pressure.

 

Trabectome

FDA-approved in 2006, the Trabectome is a MIGS device used for the treatment of primary open-angle glaucoma. The Trabectome is an electrocautery device that removes part of the meshwork from your eye's natural drainage system. By creating a larger opening in the meshwork, this procedure enlarges your eye's natural outflow channel, thus decreasing internal eye pressure.

 

The Omni360 Glaucoma Treatment System

This system combines two MIGS procedures in one surgery. First, it creates a new internal channel for shunting fluid from within your eye and directing it out through your eye's natural drainage system. Secondly, it enlarges the natural opening from your eye's drainage system to the primary canal through which fluid exits your eye (called Schlemm's canal).

 

Advanced glaucoma technology for redirecting excess ocular fluid 

For patients who don’t benefit from or can’t have a drainage procedure, fluid redirection can help reduce eye pressure. One option for redirecting excess ocular fluid is the XEN Gel Stent.

 

What is the XEN Gel Stent?

This is a stent device made of a soft gel material the size of an eyelash. The goal of the stent is to redirect excess ocular fluid out of your eye. 

 

It is placed through the eyewall without requiring an incision in the conjunctiva (the clear membrane covering the white of your eye). It is designed to stay in your eye permanently. The XEN stent is placed in the front of your eye to shunt excess ocular fluid from within your eye to a subconjunctival space.

 

Interventions that decrease ocular fluid production 

Another way to prevent vision loss from glaucoma and reduce IOP is to decrease ocular fluid production. One way to do that is via Endocyclophotocoagulation.

 

What is Endocyclophotocoagulation?

Endocyclophotocoagulation, also known as ECP, decreases eye pressure by decreasing overall fluid production. ECP utilizes a miniature camera placed inside the eye to view the ciliary body cells that produce ocular fluid. 

 

These cells are then treated with a very precise laser beam to decrease their fluid production activity, thereby leading to lower intraocular pressure. ECP can be used for both open-angle or angle-closure glaucoma patients and takes about five minutes per eye.

 

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Which glaucoma surgery is right for me?

During your examination, our eye doctor will review the options available from our large toolkit of procedures. The doctor will review your type of glaucoma, the stage of your glaucoma, eye anatomy, and other medical conditions you may have. Taking all of these factors into account — along with the safety profile of the procedures — our glaucoma expert will choose the best option for you.

 

MIGS procedures are frequently performed in combination with cataract surgery for the appropriate patients. MIGS performed at the Assil Gaur Eye Institute include iStent, OMNI 360, XEN gel stent, and ECP. 

 

Trust Assil Gaur Eye Institute’s glaucoma specialists 

Assil Gaur Eye Institute adheres to the highest standards of ophthalmology and patient care in the country. They have assembled a team of top ophthalmologists from around the country who continue AGEI’s tradition of offering patients the highest quality of specialist eye care and postoperative support.

 

Our Director of Glaucoma Services, Dr. Avneet K. Sodhi Gaur, is a board-certified, fellowship-trained cataract and glaucoma specialist and a member of ‌the American Academy of Ophthalmology.

 

She has extensive experience in conventional glaucoma laser treatments and surgical procedures, such as trabeculectomy and glaucoma drainage implants. Dr. Gaur also performs state-of-the-art minimally invasive glaucoma procedures, including iStent, iStent inject, Hydrus, ECP, OMNI 360, and Xen gel stent

 

To request an appointment, please call (866) 945-2745 or request your appointment online.

 

We are conveniently located for patients throughout Southern California and the Los Angeles area in or near Beverly Hills, Santa Monica, West Los Angeles, West Hollywood, Culver City, Hollywood, Venice, Marina del Rey, Malibu, Manhattan Beach, and downtown Los Angeles.

 

REFERENCES

Davids A-M, Pahlitzsch M, Boeker A, Winterhalter S, Maier-Wenzel A-K, Klamann M. Ab interno canaloplasty (ABiC)—12-month results of a new minimally invasive glaucoma surgery (MIGS). Graefe's Archive for Clinical and Experimental Ophthalmology. 2019;257:1947-1953.

 

Grover D.S., Fellman R.L. Gonioscopy-assisted transluminal trabeculotomy (GATT): Thermal suture modification with a dye-stained rounded tip. J. Glaucoma. 2016;25:501–504. doi: 10.1097/IJG.0000000000000325.

 

Lass J.H., Benetz B.A., He J., Hamilton C., Von Tress M., Dickerson J., Lane S. Corneal endothelial cell loss and morphometric changes 5 years after phacoemulsification with or without CyPass Micro-Stent. Am. J. Ophthalmol. 2019;208:211–218. doi: 10.1016/j.ajo.2019.07.016.

 

Saheb H, Ahmed I. Micro-Invasive glaucoma surgery: current perspectives and future directions. Curr Opin Ophthalmol. 2012;23:96-104.

SooHoo J.R., Seibold L.K., Radcliffe N.M., Kahook M.Y. Minimally invasive glaucoma surgery: Current implants and future innovations. Can. J. Ophthalmol. 2014;49:528–533. doi: 10.1016/j.jcjo.2014.09.002. 

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